{"id":88461,"date":"2025-02-06T17:40:35","date_gmt":"2025-02-06T17:40:35","guid":{"rendered":"https:\/\/qorebiotechnologies.com\/?page_id=88461"},"modified":"2025-05-27T18:46:51","modified_gmt":"2025-05-27T18:46:51","slug":"qore-biotech","status":"publish","type":"page","link":"https:\/\/qorebiotechnologies.com\/","title":{"rendered":"Qore Biotech"},"content":{"rendered":"

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Qore Biotechnologies<\/h4>\n

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Revolutionising<\/h1>\n

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Cardiovascular Translational Research using Living Myocardial Slices<\/h1>\n

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Novel organotypic in-vitro platform to investigate human cardiac function<\/p>\n

[\/et_pb_text][et_pb_button button_url=”#Contact” button_text=”Get \u0131n touch” _builder_version=”4.27.4″ _module_preset=”default” custom_button=”on” button_text_size=”13px” button_text_color=”#252942″ button_bg_color=”#FFFFFF” button_border_radius=”25px” button_letter_spacing=”1px” button_font=”Work Sans|||on|||||” button_icon=”||fa||900″ button_on_hover=”off” custom_margin=”0px||0px|281px|false|false” custom_margin_tablet=”0px||0px|242px|false|false” custom_margin_phone=”|||0px|false|false” custom_margin_last_edited=”on|tablet” custom_padding=”14px|44px|14px|30px|false|false” animation_style=”slide” animation_direction=”bottom” animation_delay=”1400ms” animation_intensity_slide=”15%” animation_speed_curve=”ease” global_colors_info=”{}” button_bg_color__hover_enabled=”on|hover” button_bg_color__hover=”#e06666″ button_bg_enable_color__hover=”on” button_text_color__hover_enabled=”on|desktop” button_text_color__hover=”#FFFFFF”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ admin_label=”About” module_id=”About” _builder_version=”4.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” width=”91%” max_width=”1247px” use_custom_width=”on” custom_width_px=”900px” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_4_font=”Work Sans|||on|||||” header_4_text_align=”left” header_4_text_color=”#111112″ header_4_font_size=”13px” header_4_letter_spacing=”1px” header_4_line_height=”0.7em” background_color=”#f5f2f0″ custom_margin=”0px||12px||false|false” custom_padding=”11px|20px|0px|20px|false|false” custom_css_main_element=”backdrop-filter: blur(4px) grayscale(92%) sepia(0%) invert(0%) brightness(100%);||display:inline-block;” border_radii=”on|50px|50px|50px|50px” global_colors_info=”{}”]<\/p>\n

ABOUT QORE<\/h4>\n

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Redefining Pre-clinical Research with Human Heart Tissue<\/h2>\n

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Qore Biotechnologies is a research team from Imperial College London and the University of Cambridge<\/strong>, participating in the BBSRC ICURe Explore programme<\/strong> to assess the market need for human-relevant preclinical models<\/strong>. Our living myocardial slices<\/strong> improve drug testing, toxicity screening, and disease modelling<\/strong>, offering a more accurate, cost-effective, and ethical alternative<\/strong> to traditional methods.<\/p>\n

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THE PROBLEM<\/h4>\n

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Inefficient and Costly Preclinical Models<\/h2>\n

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Current preclinical models for cardiovascular drug development, such as stem cell-derived cardiomyocytes and animal models, often lack the physiological complexity, cellular maturity, and relevance of the adult human myocardium. As a result, clinical trial success rates remain as low as 6%, despite over $700 million being spent on preclinical cardiovascular research per single drug.<\/p>\n

We believe that integrating living myocardial slices into the preclinical research pipeline can significantly reduce costs and improve predictability by utilising adult human heart tissue for highly translatable drug screening, toxicology testing, and validation. This approach not only minimises costs associated with stem cell and animal studies but also streamlines drug development by allowing researchers to focus resources on the most promising therapeutic candidates, reducing time wasted on non-relevant models and enhancing overall efficiency.<\/p>\n

[\/et_pb_text][et_pb_button button_url=”https:\/\/research.typeform.com\/to\/XqBtksD3″ url_new_window=”on” button_text=”TAKE OUR SURVEY” button_alignment=”left” button_alignment_tablet=”center” button_alignment_phone=”center” button_alignment_last_edited=”on|tablet” _builder_version=”4.27.4″ _module_preset=”default” custom_button=”on” button_text_size=”13px” button_text_color=”#252942″ button_bg_color=”#FFFFFF” button_border_color=”#252942″ button_border_radius=”25px” button_letter_spacing=”1px” button_font=”Work Sans|||on|||||” button_icon=”||fa||900″ button_on_hover=”off” custom_margin=”29px||0px||false|false” custom_margin_tablet=”20px||0px||false|false” custom_margin_phone=”20px||0px||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”14px|44px|14px|30px|false|false” global_colors_info=”{}” button_bg_color__hover_enabled=”on|desktop” button_bg_color__hover=”#e06666″ button_bg_enable_color__hover=”on” button_text_color__hover_enabled=”on|hover” button_text_color__hover=”#FFFFFF” button_border_color__hover_enabled=”on|hover” button_border_color__hover=”RGBA(255,255,255,0)”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Split Section” _builder_version=”4.16″ custom_padding=”0px||0px|” animation_style=”fold” animation_direction=”bottom” animation_intensity_fold=”4%” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” module_class=” et_pb_row_fullwidth” _builder_version=”4.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” width=”100%” width_tablet=”100%” width_phone=”” width_last_edited=”on|desktop” max_width=”100%” max_width_tablet=”100%” max_width_phone=”” max_width_last_edited=”on|desktop” custom_margin=”|||” custom_padding=”0px||0px|” make_fullwidth=”on” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ background_color=”#f4f4f4″ background_position=”top_left” custom_padding=”8%|6%|8%|16%” custom_padding_tablet=”” custom_padding_phone=”80px|10%|80px|10%” custom_padding_last_edited=”on|desktop” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text module_id=”Solution” _builder_version=”4.27.4″ _module_preset=”default” header_4_font=”Work Sans|||on|||||” header_4_text_align=”left” header_4_text_color=”#111112″ header_4_font_size=”13px” header_4_letter_spacing=”1px” header_4_line_height=”0.7em” background_color=”rgba(17,17,18,0.18)” custom_margin=”0px||12px|-65px|false|false” custom_margin_tablet=”0px||12px|-65px|false|false” custom_margin_phone=”0px||9px|-16px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”11px|20px|0px|20px|false|false” custom_css_main_element=”backdrop-filter: blur(4px) grayscale(92%) sepia(0%) invert(0%) brightness(100%);||display:inline-block;” border_radii=”on|50px|50px|50px|50px” global_colors_info=”{}”]<\/p>\n

OUR SOLUTION<\/h4>\n

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Living Myocardial Slices<\/h2>\n

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Living myocardial slices provide a highly predictive, efficient, and cost-effective solution for cardiovascular drug development by using adult human heart tissue. Unlike traditional preclinical models, our platform can obtain human-relevant data which could potentially reduce the risk of clinical trial failures and lower the costs associated with stem cells and animal research. By offering a service providing drug screening, toxicology testing, and functional assessments, we eliminate the need for customers to establish in-house platforms. Additionally, our adaptable system allows long-term culture of human tissue to mimic chronic cardiac diseases, the possibility to recreate disease models in vitro, providing a versatile and high-impact solution for accelerating cardiovascular drug discovery.<\/p>\n

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INDUSTRIES<\/h4>\n

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Who We Serve<\/h2>\n

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Improving drug efficacy testing and reducing failure rates.<\/p>\n

[\/dipl_interactive_image_card][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.25.1″ _module_preset=”default” border_radii=”on|5px|5px|5px|5px” global_colors_info=”{}”][dipl_interactive_image_card title=”Contract Research Organisations (CROs)” image=”https:\/\/qorebiotechnologies.com\/wp-content\/uploads\/2025\/02\/CRO.png” select_layout=”effect-sadie” image_opacity=”0.8″ overlay_color=”rgba(0,0,0,0.56)” admin_label=”Marketing” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ title_font=”Work Sans||||||||” title_text_color=”#FFFFFF” title_font_size=”26px” content_font=”Work Sans||||||||” content_font_size=”19px” locked=”off” global_colors_info=”{}”]<\/p>\n

Enhancing preclinical drug validation with human-relevant models.<\/p>\n

[\/dipl_interactive_image_card][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.25.1″ _module_preset=”default” border_radii=”on|5px|5px|5px|5px” global_colors_info=”{}”][dipl_interactive_image_card title=”Academic Research Institutions” image=”https:\/\/qorebiotechnologies.com\/wp-content\/uploads\/2025\/02\/ACADEMIC.png” select_layout=”effect-sadie” image_opacity=”0.8″ overlay_color=”rgba(0,0,0,0.56)” admin_label=”Networking” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ title_font=”Work Sans||||||||” title_text_color=”#FFFFFF” title_font_size=”26px” content_font=”Work Sans||||||||” content_font_size=”21px” locked=”off” global_colors_info=”{}”]<\/p>\n

Supporting high-impact cardiovascular research and disease modelling.<\/p>\n

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Enabling safer toxicity and cardiotoxicity screening.<\/p>\n

[\/dipl_interactive_image_card][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.25.1″ _module_preset=”default” border_radii=”on|5px|5px|5px|5px” global_colors_info=”{}”][dipl_interactive_image_card title=” Food & Nutraceutical Companies” image=”https:\/\/qorebiotechnologies.com\/wp-content\/uploads\/2025\/02\/CHEMICAL-1.png” select_layout=”effect-sadie” image_opacity=”0.8″ overlay_color=”rgba(0,0,0,0.56)” admin_label=”Marketing” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ title_font=”Work Sans||||||||” title_text_color=”#FFFFFF” title_font_size=”26px” content_font=”Work Sans||||||||” content_font_size=”20px” locked=”off” global_colors_info=”{}”]<\/p>\n

Testing the effects of functional ingredients on heart health.<\/p>\n

[\/dipl_interactive_image_card][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.25.1″ _module_preset=”default” border_radii=”on|5px|5px|5px|5px” global_colors_info=”{}”][dipl_interactive_image_card title=” Fitness & Sports Science” image=”https:\/\/qorebiotechnologies.com\/wp-content\/uploads\/2025\/02\/Sport.png” select_layout=”effect-sadie” image_opacity=”0.8″ overlay_color=”rgba(0,0,0,0.56)” admin_label=”Networking” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ title_font=”Work Sans||||||||” title_text_color=”#FFFFFF” title_font_size=”26px” content_font=”Work Sans||||||||” content_font_size=”20px” locked=”off” global_colors_info=”{}”]<\/p>\n

Evaluating supplements and interventions for cardiovascular performance.<\/p>\n

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TAKE OUR SURVEY<\/h4>\n

[\/et_pb_text][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_2_font=”Work Sans||||||||” header_2_text_align=”center” header_2_text_color=”#111112″ header_2_font_size=”54px” header_2_line_height=”1.1em” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”2%” animation_speed_curve=”ease” header_2_font_size_tablet=”54px” header_2_font_size_phone=”30px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

Share Your Insights<\/h2>\n

[\/et_pb_text][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font=”Roboto Flex||||||||” text_text_color=”#666666″ text_font_size=”16px” text_line_height=”1.6em” text_orientation=”center” custom_margin=”0px||25px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”]<\/p>\n

We are conducting market research to understand the challenges faced in cardiovascular drug development, toxicity testing, and disease modelling<\/strong>. Your insights will help us assess the demand for human-relevant preclinical models<\/strong> and refine our technology to meet industry needs.<\/p>\n

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Who Should Participate?<\/h3>\n

[\/et_pb_text][et_pb_blurb title=”Pharmaceutical & Biotech Companies” use_icon=”on” font_icon=”N||divi||400″ icon_color=”#e06666″ icon_placement=”left” image_icon_width=”22px” _builder_version=”4.27.4″ _module_preset=”default” header_font=”Roboto Flex||||||||” header_text_align=”left” header_text_color=”#03251e” header_font_size=”16px” header_line_height=”1.5em” image_icon_custom_margin=”0px||0px||false|false” image_icon_custom_padding=”0px||0px||false|false” custom_margin=”0px||2px|20px|false|false” custom_margin_tablet=”0px||2px|20px|false|false” custom_margin_phone=”0px||2px|0px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”0px||0px||false|false” animation=”off” custom_css_blurb_title=”margin-left:-10px;” custom_css_blurb_content=”margin:0px;” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Contract Research Organisations (CROs)” use_icon=”on” font_icon=”N||divi||400″ icon_color=”#e06666″ icon_placement=”left” image_icon_width=”22px” 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custom_margin_phone=”0px||2px|0px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”0px||0px||false|false” animation=”off” custom_css_blurb_title=”margin-left:-10px;” custom_css_blurb_content=”margin:0px;” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Nutraceutical & Sports Science Sectors” use_icon=”on” font_icon=”N||divi||400″ icon_color=”#e06666″ icon_placement=”left” image_icon_width=”22px” _builder_version=”4.27.4″ _module_preset=”default” header_font=”Roboto Flex||||||||” header_text_align=”left” header_text_color=”#03251e” header_font_size=”16px” header_line_height=”1.5em” image_icon_custom_margin=”0px||0px||false|false” image_icon_custom_padding=”0px||0px||false|false” custom_margin=”0px||2px|20px|false|false” custom_margin_tablet=”0px||2px|20px|false|false” custom_margin_phone=”0px||2px|0px|false|false” custom_margin_last_edited=”on|phone” custom_padding=”0px||0px||false|false” animation=”off” custom_css_blurb_title=”margin-left:-10px;” 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EXPERT TEAM<\/h4>\n

[\/et_pb_text][et_pb_text _builder_version=”4.24.3″ _module_preset=”default” header_2_font=”Work Sans||||||||” header_2_text_align=”left” header_2_text_color=”#111112″ header_2_font_size=”54px” header_2_line_height=”1.1em” custom_margin=”0px||10px||false|false” custom_padding=”0px||0px||false|false” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”2%” animation_speed_curve=”ease” header_2_font_size_tablet=”54px” header_2_font_size_phone=”30px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

Meet our team<\/h2>\n

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Our multidisciplinary team combines expertise in cardiovascular science, biotechnology, and commercialisation to bring cutting-edge research into real-world applications.<\/p>\n

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Laura Nicastro<\/h3>\n

[\/et_pb_text][et_pb_social_media_follow icon_color=”#FFFFFF” use_icon_font_size=”on” _builder_version=”4.27.4″ _module_preset=”default” background_enable_color=”off” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” border_radii=”on|15px|15px|15px|15px” global_colors_info=”{}”][et_pb_social_media_follow_network social_network=”linkedin” url=”https:\/\/www.linkedin.com\/in\/laura-nicastro09\/)%20″ _builder_version=”4.27.4″ _module_preset=”default” background_color=”#007bb6″ global_colors_info=”{}” follow_button=”off” url_new_window=”on”]linkedin[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.24.3″ _module_preset=”default” transform_translate_linked__hover=”off” custom_padding=”|15px||15px|false|false” custom_padding_tablet=”|15px||15px|false|false” custom_padding_phone=”|0px||0px|false|false” custom_padding_last_edited=”on|phone” global_colors_info=”{}” transform_styles__hover_enabled=”on|hover” transform_scale__hover_enabled=”on|hover” transform_translate__hover_enabled=”on|hover” transform_rotate__hover_enabled=”on|desktop” transform_skew__hover_enabled=”on|desktop” transform_origin__hover_enabled=”on|desktop” transform_translate__hover=”0px|-5px”][et_pb_blurb title=”CSO” use_icon=”on” font_icon=”||fa||900″ icon_color=”#e06666″ icon_placement=”left” image_icon_width=”7px” _builder_version=”4.27.4″ _module_preset=”default” header_font=”Work Sans|||on|||||” header_text_align=”left” header_text_color=”rgba(3,37,30,0.8)” header_font_size=”13px” header_letter_spacing=”1px” header_line_height=”1.2em” image_icon_custom_margin=”4px||0px||false|false” image_icon_custom_padding=”0px||0px||false|false” custom_margin=”0px||5px||false|false” custom_margin_tablet=”60px||5px||false|false” custom_margin_phone=”50px||5px||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”0px||0px||false|false” animation=”off” link_option_url=”#” custom_css_blurb_title=”margin-left:-32px;” custom_css_blurb_content=”margin:0px;” global_colors_info=”{}”][\/et_pb_blurb][et_pb_image src=”https:\/\/qorebiotechnologies.com\/wp-content\/uploads\/2025\/02\/1517278397913.jpg” title_text=”1517278397913″ url=”#” force_fullwidth=”on” _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”0px||20px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_font=”Work Sans||||||||” header_3_text_align=”left” header_3_text_color=”#111112″ header_3_font_size=”24px” header_3_line_height=”1.2em” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” link_option_url=”#” global_colors_info=”{}”]<\/p>\n

Barrett Downing<\/h3>\n

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Franklin Lo<\/h3>\n

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Professor Cesare Terracciano<\/span><\/h3>\n

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Reach Us<\/h1>\n

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Have questions or want to learn more about our work at Qore Biotechnologies<\/strong>? Fill out the form below, and our team will get back to you as soon as possible.<\/p>\n

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ln397@cam.ac.uk<\/a><\/p>\n

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